| Overall | Pct | Streak | Conf. | Pct | 5-4 | .556 | L2 | 2-4 | .333 |
| Date | Opponent | Location | Coverage | Time/Result | | Sep. 4, 2021 | ERSKINE | SALISBURY |    | 37-27 W | Recap | Box | | Sep. 11, 2021 | WINSTON-SALEM ST. (Parking Info) | SALISBURY | | 28-6 W | Recap | Box | | Sep. 18, 2021 | BARTON | SALISBURY | | 17-10 W | Recap | Box | | Sep. 25, 2021 | @ Wingate, ccd.* | WIngate,NC | | 6 p.m. | Recap | Box | | Oct. 2, 2021 | LIMESTONE, ccd.* | SALISBURY | | 1 p.m. | Recap | Box | | Oct. 9, 2021 | CARSON-NEWMAN* | SALISBURY | | 33-27 W | Recap | Box | | Oct. 16, 2021 | @ Newberry* | Newberry,SC | | 7-14 L | Recap | Box | | Oct. 23, 2021 | @ Mars Hill* | Mars Hill,NC | | 14-31 L | Recap | Box | | Oct. 30, 2021 | TUSCULUM* | SALISBURY | | 31-28 W | Recap | Box | | Nov. 6, 2021 | UVA WISE* | SALISBURY | | 7-30 L | Recap | Box | | Nov. 13, 2021 | @ Lenoir-Rhyne* | Hickory,NC | | 3-56 L | Recap | Box | | Mar. 17, 2022 | Spring Practice | Shuford Stadium | | 6 p.m. | Recap | Box | | Mar. 18, 2022 | Spring Practice | Shuford Stadium | | 4 p.m. | Recap | Box | | Mar. 19, 2022 | Spring Practice | Shuford Stadium | | 9 a.m. | Recap | Box | | Mar. 21, 2022 | Spring Practice | Shuford Stadium | | 4 p.m. | Recap | Box | | Mar. 23, 2022 | Spring Practice | Shuford Stadium | | 6 a.m. | Recap | Box | | Mar. 25, 2022 | Spring Practice | Shuford Stadium | | 4 p.m. | Recap | Box | | Mar. 26, 2022 | Spring Practice | Shuford Stadium | | 9 a.m. | Recap | Box | | Mar. 28, 2022 | Spring Practice | Shuford Stadium | | 4 p.m. | Recap | Box | | Mar. 30, 2022 | Spring Practice | Shuford Stadium | | 4 p.m. | Recap | Box | | Apr. 1, 2022 | Spring Practice | Shuford Stadium | | 4 p.m. | Recap | Box | | Apr. 9, 2022 | Spring Game | Shuford Stadium | | 10 a.m. | Recap | Box |
Home dates are in bold.
* - indicates South Atlantic Conference event
All times are local.
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